This link states the following, it's the result from a study; Docs should know all this cold, if it's found by google ... anyhow, trying just now to gain a foothold on the variations in chemo treatments and their success rates: this post is negative against doxorubicin, but that's a qualified negativeIt's title is:
Additional chemotherapy with doxorubicin marginally improves tumour response but increases side effects with no improvement in survival
Doxorubicin is commonly used as palliative chemotherapy for patients with advanced or metastatic soft tissue sarcoma (cancer of muscle/tendon/fat/blood vessel). This review was conducted to find out if combining doxorubicin with other drugs is more effective than doxorubicin alone. Eight studies were considered together, which showed if combination chemotherapy is given: (1) tumour shrinkage was marginally better than in patients treated with doxorubicin alone; (2) survival was no different; and (3) side effects were worse than for patients treated with doxorubicin alone
Compared to single-agent doxorubicin, the combination chemotherapy regimens evaluated, given in conventional doses, produced only marginal increases in response rates, at the expense of increased toxic effects and with no improvements in overall survival.
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